Breakthrough Collaboratives are increasingly seen as promising strategies for advancing and spreading evidence-based interventions and transforming practice at scale. Most of the common professional knowledge about breakthroughs draws from IHI’s Breakthrough Collaborative model, but through this interactive session, participants will engage with design dilemmas related to launching and leading education-focused collaboratives. Participants will leave with practical insights about our shared opportunity to build requisite professional knowledge and supports for using this model to scale effective practices.